The widely-used heartburn medication Zantac is facing scrutiny as several pharmacies opt to remove it from their shelves, fueled by findings suggesting it may harbor traces of a cancer-associated chemical. Although Zantac has not faced an official recall, the drug has come under fire following a September alert from the FDA, which detected low levels of NDMA, a substance deemed a “probable carcinogen” linked to certain cancers. This chemical was discovered in various medications containing ranitidine, the active ingredient in Zantac and its generic counterparts, and has previously caused recalls of numerous blood pressure drugs.
Currently, the FDA is conducting an investigation into the matter. They have urged manufacturers of Zantac and its generics to test their products for NDMA and submit the results, but have not yet recommended that consumers cease usage of the medication. In their words, “The agency is working with international regulators and industry partners to determine the source of this impurity in ranitidine. The agency is examining levels of NDMA in ranitidine and evaluating any possible risk to patients.”
In a proactive move, major pharmacy chains like Rite-Aid, Walgreens, and CVS have chosen to halt the sale of Zantac and its generics, citing precautionary measures. CVS has publicly stated that they are making this choice “out of an abundance of caution” and are offering refunds for customers who have purchased the product. While there is no formal recall, generic manufacturers Apotex and Sandoz have opted to voluntarily withdraw their versions of the medication.
Zantac has long been a go-to option for many, particularly for pregnant women and new moms grappling with heartburn, making this development quite alarming. However, until the FDA issues specific guidance on continued use, there’s no need for panic. If you have concerns, it’s wise to consult your healthcare provider about alternative heartburn medications—there are plenty of safe and effective options available.
And speaking of options, for those considering starting a family, check out our guide on at-home insemination kits for more information on how to navigate this journey. You can also explore resources on fertility treatments at March of Dimes to better understand your choices.
In summary, while Zantac remains available for now, its presence on store shelves is dwindling due to potential safety issues. Consumers are encouraged to stay informed and consult with their healthcare providers about alternatives.

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