In a significant study conducted by the CDC, it was revealed that both the Pfizer and Moderna COVID-19 vaccines are remarkably effective at preventing infections among healthcare workers and first responders. The findings indicate a 90% reduction in infection rates two weeks after the second dose. After enduring over a year of pandemic struggles, this news is a much-needed breath of fresh air.
The research shows that these vaccines are effective at curbing both symptomatic and asymptomatic infections, highlighting their efficacy outside of controlled clinical trial environments. This is especially encouraging. One dose of the vaccine was shown to prevent 80% of infections, with the second dose increasing that effectiveness to 90% after two weeks.
This is particularly significant given concerns in the scientific community regarding whether vaccinated individuals could still transmit the virus through asymptomatic infections. The study also addressed fears about the vaccines’ effectiveness against emerging COVID-19 variants, revealing that they maintained their protective capabilities even as various concerning strains circulated during the study period, which ran from December 14, 2020, to March 13, 2021.
The participant group consisted of 3,950 individuals at high risk of exposure to the virus, including healthcare workers and first responders, none of whom had previously contracted COVID-19. The results were promising, with 62.8% of participants having received both doses, and 12.1% having received one dose. Participants self-collected nasal swabs weekly for PCR testing, the most reliable form of COVID-19 testing, enabling researchers to identify both symptomatic and asymptomatic cases. Notably, 58% of infections were discovered before participants exhibited any symptoms, and only 10.2% of infections were asymptomatic.
Here’s the impressive takeaway: among fully vaccinated participants, there were only 0.04 infections per 1,000 person-days, meaning just 0.04 infections in a day for every 1,000 vaccinated individuals. For those with just one shot, the rate was still low at 0.19 infections per 1,000 person-days.
In summary, this study underscores that national vaccination efforts are proving effective, according to CDC Director Dr. Rochelle P. Walensky.
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In summary, the CDC study highlights the impressive effectiveness of the Pfizer and Moderna vaccines in real-world scenarios, offering hope in the ongoing battle against COVID-19.

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